How to set smtp server
May 28, 2017 · In IIS 6 Manager, expand the server name, in my example below it is VS11APP003, then right-click on [SMTP Virtual Server #1] and select Properties: 14. In the General tab, unless you want the SMTP Server to use a specific IP address, leave the settings as they are so that the IP address is set to (All Unassigned): 15.